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To assess the therapeutic effects of oral zileuton tablets combined with low-dose beclomethasone compared to doubling the dose of beclomethasone, in improving lung function and reducing asthma symptoms.Randomized, active-control, double-blind, parallel, multi-center study of zileuton (400 or 600mg QID)+200μg beclomethasone dipropionate (BDP) BID versus placebo+BDP 400μg BID in asthmatics with baseline...
The magnitude of improvement of respiratory symptoms (RS) and expiratory flows (EF) following corticosteroid treatment may vary from one asthmatic patient to another. The distribution of ratio of improvement of the above parameters was assessed in 937 patients with asthma of variable severity who took part in three clinical trials comparing the effects of chlorofluorocarbon-propelled beclomethasone...
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