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Mambas, African snakes of the genus Dendroaspis, produce several types of toxins that are of pharmacological interest. The novel muscarinic toxin-1 (MT-1), from the green mamba Dendroaspis angusticeps, binds specifically to muscarinic M 1 receptors in homogenates of rat cerebral cortex. Iodination of the toxin, 125 I-muscarinic toxin-1 ( 125 I-MT-1), renders...
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