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Abstract: Skin stress response system (SSRS) involves corticotropin‐releasing hormone (CRH) and proopiomelanocortin (POMC)‐derived peptides, such as adrenocorticotropic hormone (ACTH), a‐melanocyte‐stimulating hormone (MSH) and b‐endorphin that are locally generated in response to locally provided stressors or proinflammatory cytokines. This system would restrict tissue damage and restore local homoeostasis...
Please cite this paper as: Vitamin C attenuates ERK signalling to inhibit the regulation of collagen production by LL‐37 in human dermal fibroblasts. Experimental Dermatology 2010; 19: e258–e264.
Abstract: Vitamin C is used as an anti‐ageing agent because of its collagen enhancing effects. The precise cellular signalling mechanism of vitamin C is not well known. Here, we investigate the profibrotic...
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