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Multiple-transgene co-integration offers a powerful means by which several transgenes can be co-expressed in mammary glands. Independent gene constructs, including bovine α-casein-hG-CSF, mWAP-hEPO, and CMV-EGFP, were co-injected into fertilized mouse eggs whereupon 32% (17/54) of the transgenic mice showed integration of all the three constructs. The co-expression ratio of hG-CSF and hEPO proteins...
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