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A series of N-((1,3-diphenyl-1H-pyrazol-4-yl)methyl)anilines were synthesized and evaluated in vitro for cytotoxicity and antiviral activity against a large panel of viruses. Most of the tested compounds interfered with RSV replication in the micromolar concentrations (EC 50 s ranging from 5μM to 28μM). SAR studies suggested that the presence of a trifluoromethyl group in R 1 abolished...
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