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The importance of NADPH oxidase (Nox) in hypoxic responses in hypoxia-sensing cells, including pulmonary artery smooth muscle cells (PASMCs), remains uncertain. In this study, using Western blot analysis we found that the major Nox subunits Nox1, Nox4, p22 phox , p47 phox , and p67 phox were equivalently expressed in mouse pulmonary and systemic (mesenteric) arteries. However,...
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