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The association between serum digoxin concentration (SDC) and outcomes in women with heart failure (HF) has not been well studied.To test the hypothesis that the effect of digoxin on outcomes in women with HF is bi-directional and dependent on SDC, as in men, and is modified by ejection fraction (EF).We studied 1366 female participants of the Digitalis Investigation Group trial in whom data on SDC...
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