Search results for: Daisuke Abe
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Metabolism of 26,26,26,27,27,27-F 6 -1α,25-dihydroxyvitamin D 3 by CYP24: species-based difference between humans and rats
Biochemical Pharmacology > 2003 > 65 > 12 > 1957-1965
The compound 26,26,26,27,27,27-F 6 -1α,25(OH) 2 D 3 is a hexafluorinated analog of the active form of Vitamin D 3 . The enhanced biological activity of F 6 -1α,25(OH) 2 D 3 is considered to be related to a decreased metabolic inactivation of the compound in target tissues such as the kidneys, small intestine, and bones. Our previous study demonstrated...
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