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Background
Supportive‐care use of granulocyte colony‐stimulating factor (G‐CSF) in pediatric acute myeloid leukemia (AML) remains controversial due to a theoretical increased risk of relapse and limited impact on neutropenic complications. We describe the use of G‐CSF in patients treated according to NOPHO‐AML 2004 and DB AML‐01 and investigated associations with relapse.
Procedure
Patients diagnosed...
The t(7;12)(q36;p13) (MNX1/ETV6) is not included in the WHO classification but has been described in up to 30% of acute myeloid leukemia (AML) in children <2 years and associated with a poor prognosis. We present the clinical and cytogenetics characteristics of AML cases with t(7;12)(p36;p13). A literature review identified 35 patients with this translocation, published between 2000 and 2015. Outcome...
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