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Protein-protein interaction network provides valuable information in adaptation and evolution of living organisms. Since metabolism is one of the most fundamental processes in the early formation of live organism, we selected metabolic proteins from MIPS function category and constructed metabolic-related protein-protein interaction network. The network has scale-free and hierarchical properties as...
Traditionally, most researches in development of new drug target focus on relationship between a target protein and a related compound by experimental or computational approaches. In addition to the translational level, it is useful tool control disease at the transcriptional level, if we identify transcription factors that regulate expression of target proteins. We introduce new methodology that...
Biological sequences such as DNA and amino acid sequences typically contain a large number of items. They have contiguous sequences that ordinarily consist of more than hundreds of frequent items. In biological sequences analysis (BSA), a frequent contiguous sequence search is one of the most important operations. Many studies have been done for mining sequential patterns efficiently. In recent years,...
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