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Our laboratory reported that Irinophore C™ (IrC™; a lipid-based nanoparticulate formulation of irinotecan) is effective against an orthotopic model of glioblastoma (GBM) and that treatment with IrC™ was associated with vascular normalization within the tumor. Here, the therapeutic effects of IrC™ when used in combination with temozolomide (TMZ) in concurrent and sequential treatment schedules were...
Hypercalcemia associated with endometrial carcinoma is rare. We report a patient with serous papillary endometrial carcinoma with paraneoplastic hypercalcemia due to parathyroid hormone-related peptide (PTHrP). To the best of our knowledge this is the first report of hypercalcemia due to PTHrP in this type of tumor.
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