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Embolization
In article number 2106865, Fiorenzo Omenetto, Rahmi Oklu, and co‐workers demonstrate a silk embolic material (represented in yellow) being released from a catheter and occluding an artery. Therapeutics within the silk embolic material (shown in blue) diffusing outside of the arterial wall achieve targeted drug delivery within the tissue parenchyma.
Embolization is a catheter‐based minimally invasive procedure that deliberately occludes diseased blood vessels for treatment purposes. A novel silk‐based embolic material (SEM) that is developed and optimized to provide tandem integration of both embolization and the delivery of therapeutics is reported. Natural silk is processed into fibroin proteins of varying lengths and is combined with charged...
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