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Variants of cancer susceptibility genes other than BRCA1/2 have been proved to be associated with increased risks of breast cancer. This study was performed to investigate the spectrum and prevalence of mutations in 10 cancer susceptibility genes in paired tumor/normal tissues of 292 unselected Chinese breast cancer patients. We performed an analysis of germline and somatic variants in ATM, CDH1,...
In the field of medical diagnostics, biomedical photoacoustics (PA) is a non-invasive hybrid optical-ultrasonic imaging modality. Due to the unique hybrid capability of optical and acoustic imaging, PA imaging has risen to the frontiers of medical diagnostic procedures such as human breast cancer detection. While conventional PA imaging has been mainly carried out by a high-power pulsed laser, an...
In Ultra-Wideband (UWB) microwave imaging for breast cancer detection, UWB pulses illuminate the breast and the echoes are processed to create images. Adoption in screening campaigns requires the development of a fully-engineered medical imaging tool. In this paper we report on our experience with the design of this kind of UWB imaging system and illustrate some of the challenges the designers have...
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