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We demonstrate an efficient method to improve the reproducibility of SERS detection by controlling the distribution of silver nanoparticles (AgNPs) using Si nanopillar arrays as space confined templates for generating AgNPs with electroless deposition. In the detection of 4-MPy, the relative standard deviation of SERS intensity is decreased to ca. 5.27% from 23.2% by using the AgNPs selectively deposited...
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