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The ATPbinding cassette transporter, ABCG2, which is expressed at high levels in the intestine and liver, functions as an efllux transporter for many drugs, including clinically used anticancer agents such as topotecan and the active metabolite of irinotecan (SN38). In this study, to elucidate the linkage disequilibrium (LD) profiles and haplotype structures of ABCG2, we have comprehensively searched...
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