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Deferoxamine is commonly used for iron-overload related diseases, its drawbacks such as instability and toxicity, however, significantly limited its utility in clinic. To address these issues, oxidation-responsive alginate-deferoxamine (Alg-DFO) conjugates were synthesized and their structure was characterized. The metabolism studies shown the conjugation of alginate significantly increased the stability...
A rapid method was developed to determine the molecular weight (M n ) of β-limit dextrin and dextrans (Leuconostoc mesenteroides) using a reducing power approach. The M n of the β-limit dextrin was also estimated from high performance liquid chromatography (HPLC). Chromatograms were pre-calibrated with the dextrans. The three dextrins had a M n of 2.09, 2.40 and 2.63×10 ...
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