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In metastatic renal cell carcinoma (mRCC) patients treated with targeted agents and their primary tumor (PT) in situ, early PT decrease in size correlates with improved overall PT response, but the effect on overall survival (OS) is unknown.To evaluate whether early PT size reduction is associated with improved OS in patients with mRCC undergoing treatment with sunitinib.We reviewed the clinical and...
The recent development of multiple targeted agents for metastatic renal cell carcinoma (mRCC) has changed the treatment paradigm; hence the benefit and optimal timing of cytoreductive nephrectomy is being reevaluated.To determine primary tumor response to treatment with targeted agents in patients with mRCC.We reviewed the clinical and radiographic data of all mRCC patients seen at our institution...
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