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An autosomal polymorphism, designated H19FR which located upstream of imprinted H19 gene, was investigated. Three allelic bands of H19FR system were detected by PCR amplification followed by constant denaturing gel electrophoresis (CDGE). In digested genomic DNA by methylation-sensitive endonuclease or McrBC, paternal or maternal allele of H19FR was selectively detectable, respectively. This parental...
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