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Electrophoretic mobility shift assays revealed minimal levels of NF-κB activity in rat distal lung epithelial cells cultured at fetal (23 mmHg) or adult alveolar (100 mmHg) PO 2 , but revealed significant activation of this transcription factor in cells exposed to a rise in PO 2 mimicking that experienced at birth. This response was entirely abolished by pretreating cells with 5 mM...
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