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Background
Kelch‐like 6 (KLHL6) is a cancer oncogene previously associated with specific human cancers, such as chronic lymphocytic leukaemia. Here, the mechanisms of KLHL6 function were explored in gastric cancer (GC) cells, in an in vivo experimental tumour model, and the prognostic value of KLHL6 analysis in GC tissue evaluated in a cohort of patients with GC.
Methods
Associations between clinicopathological...
BackgroundThe hypermethylation of ring finger protein (RNF) 180 DNA promoter is significantly associated with lymph node metastasis of gastric cancer. The present study explored the potential mechanism of RNF180‐regulated lymph node metastasis of gastric cancer.
MethodsAssociations between clinicopathological and survival data and RNF180 expression in gastric cancer tissues were analysed. The effects...
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