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Psoriasis has long been considered as a complex disease, and gene–gene or gene–environment interactions may jointly influence the etiology for psoriasis.We evaluated the associations of single nucleotide polymorphisms (SNPs) in MHC region, and determined the epistasis and combined effects of MHC locus and IL12B, LCE on risk for psoriasis.We genotyped SNP rs1265181 (MHC) in 5067 cases and 6404 controls,...
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