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The long-term effects of octreotide, thesynthetic analog of the hormone somatostatin, on acuteexperimental pancreatitis were studied. Acutepancreatitis was induced in rats by intraparenchymalinjections of 0.5 ml 5% or 10% sodium taurocholate.Octreotide (10 mg/kg/day, subcutaneously), or salineinjections as controls, were started four hours later,and their effects were assessed 30, 60, and 90 daysafter...
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