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The precursors of functional biomolecules in living cells are synthesized in a bottom‐up manner and subsequently activated by modification into a delicate structure with near‐atomic precision. DNA origami technology provides a promising way to mimic the synthesis of precursors, although mimicking the modification process is a challenge. Herein, a DNA paper‐cutting (DNA kirigami) method to trim origami...
Self‐assembled nanostructures based on biomolecules (e.g., proteins and amino acids) and metal ions have promising applications in mimicking the nanostructure, properties, and functions of natural enzymes. Herein, a metal ion‐mediated self‐assembly method for constructing catalytically active Cu‐wool‐keratin (CuWK) two‐dimensional nanozymes is presented. Specifically, by introducing copper ions as...
Owing to the increasing power density of miniaturized and high‐frequency electronic devices, flexible thermal interface materials (TIMs) with the electromagnetic interference (EMI) shielding property are in urgent demand to maintain the system performance and reliability. Recently, carbon‐based TIMs receive considerable attention due to the ultrahigh intrinsic thermal conductivity (TC). However, the...
Hepatocellular carcinoma (HCC) is one of the most fatal malignancies with few effective treatment options all around the world. The efficacy of the arisen immune checkpoint therapy is still uncertain due to local immunosuppression. In order to further overcome T cell suppression in the tumor immune microenvironment while promoting the immune response of antigen‐presenting cells, a biointerfacing antagonizing...
Biointerfacing Nanoparticles
In article number 2105237, Dong‐Sheng Huang, Tian Yang, and co‐workers develop a strategy of targeting therapeutic nanoparticles effectively reversing the immune‐inhibiting microenvironment for enhanced PD‐L1 checkpoint combination therapy. The platelet membrane cloaked nanoparticles activate the CD8+ T lymphocytes and antigen presentation of dendritic cells as well as...
The rational synthesis of single‐layer noble metal directly anchored on support materials is an elusive target to accomplish for a long time. This paper reports well‐defined single‐layer Pt (Pt‐SL) clusters anchored on ultrathin TiO2 nanosheets—as a new frontier in electrocatalysis. The structural evolution of Pt‐SL/TiO2 via self‐assembly of single Pt atoms (Pt‐SA) is systematically recorded. Significantly,...
Nucleic acid‐based macromolecules have paved new avenues for the development of therapeutic interventions against a spectrum of diseases; however, their clinical translation is limited by successful delivery to the target site and cells. Therefore, numerous systems have been developed to overcome delivery challenges to nucleic acids. From the viewpoint of clinical translation, it is highly desirable...
In article number 1804855, Xingmei Guo, Tongxiang Fan, and co‐workers synthesize biomorphic CoJNJC/CoOx composite with micro‐ellipsoidal structure by using natural chloroplasts containing big amounts of chlorophylls both as template and porphyrin source. The unique synergistic effect between CoJNJC and CoOx, together with efficient bio‐architecture, leads to excellent electrocatalytical performance...
Natural chloroplasts containing big amounts of chlorophylls (magnesium porphyrin, Mg‐Chl) are employed both as template and porphyrin source to synthesize biomorphic CoNC/CoOx composite as electrocatalyst for the oxygen reduction reaction (ORR). Cobalt‐substituted chlorophyll derivative (Co‐Chl) in chloroplasts is first obtained by successively rinsing in hydrochloric acid and cobalt acetate solutions...
LiV3O8 nanorods with controlled size are successfully synthesized using a nonionic triblock surfactant Pluronic‐F127 as the structure directing agent. X‐ray diffraction, scanning electron microscopy, and transmission electron microscopy techniques are used to characterize the samples. It is observed that the nanorods with a length of 4–8 µm and diameter of 0.5–1.0 µm distribute uniformly. The resultant...
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