Search results for: Jian-Jun Guo

Items from 1 to 20 out of 25 results

article

Shear strength of sandstone–mudstone particle mixture from direct shear test

Jun-jie Wang, Jian-jun Guo, Ji-ping Bai, Xiao Wu

Environmental Earth Sciences > 2018 > 77 > 12 > 1-12

The mixture mixed by crushed sandstone and mudstone particles are gradually used as a kind of fillers in geotechnical engineering. However, the engineering practice goes ahead of the theory, the engineering features of this particle mixture have not been well revealed. Based on series of direct shear tests in laboratory, shear strength of the sandstone–mudstone particle mixture and its influencing...

article

Ecological risk assessment of the Gannan Plateau, northeastern Tibetan Plateau

Dong-xia Yue, Jian-jun Zeng, Chao Yang, Ming-liang Zou, more

Journal of Mountain Science > 2018 > 15 > 6 > 1254-1267

Desertification, soil salinization and grassland degradation are the major environmental hazards faced by the Gannan Plateau, northeastern Tibetan Plateau. Ecological risk assessment plays an important role in formulating environmental management strategies yet little attention to this region. In this study, we established an ecological risk assessment index system based on 30 evaluation indices in...

article

Risk Factors, Clinical Features and Prognosis for Subtypes of Ischemic Stroke in a Chinese Population

Ya-fu Tan, Li-xuan Zhan, Xiao-hui Chen, Jian-jun Guo, more

Current Medical Science > 2018 > 38 > 2 > 296-303

Summary It is unanimously accepted that stroke is a highly heterogeneous disorder. Different subtypes of ischemic stroke may have different risk factors, clinical features, and prognoses. The aim of this study was to evaluate the risk factors, clinical characteristics, and prognoses of different subtypes of ischemic stroke defined by the Trial of ORG10172 in Acute Stroke Treatment (TOAST) criteria...

article

Pathogenic differences of the entomopathogenic fungus Isaria cateniannulata to the spider mite Tetranychus urticae (Trombidiformes: Tetranychidae) and its predator Euseius nicholsi (Mesostigmata: Phytoseiidae)

Xiao-na Zhang, Jian-jun Guo, Xiao Zou, Dao-chao Jin

Experimental and Applied Acarology > 2018 > 75 > 1 > 69-84

Isaria cateniannulata and Euseius nicholsi are two important biological control agents currently being used in many areas of China to control a variety of pests. In order to determine the possibility of a concomitant application with the two agents in a biocontrol program involving the two-spotted spider mite, Tetranychus urticae, we quantified the pathogenicity of a strain of I. cateniannulata (08XS-1)...

article

The potential of microRNAs as human prostate cancer biomarkers: A meta‐analysis of related studies

Chun‐Jiao Song, Huan Chen, Li‐Zhong Chen, Guo‐Mei Ru, more

Journal of Cellular Biochemistry > 119 > 3 > 2763 - 2786

Prostate cancer (PC) is a very important kind of male malignancies. When PC evolves into a stage of hormone resistance or metastasis, the fatality rate is very high. Currently, discoveries and advances in miRNAs as biomarkers have opened the potential for the diagnosis of PC, especially early diagnosis. miRNAs not only can noninvasively or minimally invasively identify PC, but also can provide the...

article

Characterization of PD-L1 expression in Chinese non-small cell lung cancer patients with PTEN expression as a means for tissue quality screening

Xu-chao Zhang, Xu Cao, Chun Sun, Zhi Xie, more

Cancer Immunology, Immunotherapy > 2018 > 67 > 3 > 471-481

The goal of this study is to evaluate PD-L1 prevalence and its association with major clinical characteristics in Chinese non-small cell lung cancer (NSCLC) patients to inform the clinical development of anti-PD1/PD-L1 agents in this population. We used phosphatase and tensin homolog (PTEN) expression through IHC as a surrogate tissue quality marker to screen surgical NSCLC samples in tissue microarray...

article

An in-vitro cocktail assay for assessing compound-mediated inhibition of six major cytochrome P450 enzymes

Jing-Jing Wang, Jian-Jun Guo, Jenny Zhan, Hai-Zhi Bu, more

Journal of Pharmaceutical Analysis > 2014 > 4 > 4 > 270-278

An efficient screening assay was developed and validated for simultaneous assessment of compound-mediated inhibition of six major human cytochrome P450 (CYP) enzymes. This method employed a cocktail of six probe substrates (i.e., phenacetin, amodiaquine, diclofenac, S-mephenytoin, dextromethorphan and midazolam for CYP1A2, 2C8, 2C9, 2C19, 2D6 and 3A4, respectively) as well as individual prototypical...

article

Properties and paper sizing application of waterborne polyurethane emulsions synthesized with isophorone diisocyanate

Yu-hua Guo, Jian-jun Guo, Hui Miao, Li-jun Teng, more

Progress in Organic Coatings > 2014 > 77 > 5 > 988-996

In this work, a two-step synthesis methodology has been used to synthesize a series of waterborne polyurethane (WPU) emulsions with isophorone diisocyanate (IPDI), poly-caprolactone diol (PCL) and dimethylol propionic acid (DMPA) as monomers and ethylenediamine (EDA) as the chain extender, respectively. The influences of the NCO/OH molar ratio, DMPA content, chemicals-adding sequence, and acetone...

article

Interleukin-1β and cyclic AMP mediate the invasion of sheared chondrosarcoma cells via a matrix metalloproteinase-1-dependent mechanism

Pu Wang, Pei-Pei Guan, Tao Wang, Xin Yu, more

BBA - Molecular Cell Research > 2014 > 1843 > 5 > 923-933

Matrix metalloproteinase-1 (MMP-1) is a potential biomarker for chondrosarcoma that is overexpressed at the invading edges of articular cartilage, and its expression correlates with poor survival rates. However, the molecular mechanisms of MMP-1 regulation and its potential contribution to chondrosarcoma cell invasion have yet to be elucidated, especially in shear-activated cells. Using molecular...

article

New striatal neurons form projections to substantia nigra in adult rat brain after stroke

Xiao Sun, Qiu-Wan Zhang, Ming Xu, Jian-Jun Guo, more

Neurobiology of Disease > 2012 > 45 > 1 > 601-609

Previous studies have demonstrated that newborn striatal neurons can functionally integrate with local neural networks in adult rat brain after injury. In the present study, we determined whether these newly generated striatal neurons can develop projections to the substantia nigra, a target of striatal projection neurons. We used 5′-bromodeoxyuridine (BrdU) and a retroviral vector expressing green...

article

Bcl-2 enhances the formation of newborn striatal long-projection neurons in adult rat brain after a transient ischemic stroke

Jian-Jun Guo, Fang Liu, Xiao Sun, Jun-Jie Huang, more

Neuroscience Bulletin > 2012 > 28 > 6 > 669-679

Objective It has been reported that B-cell lymphoma 2 (Bcl-2) enhances neurogenesis as well as supporting axonal growth after injury. In the present study, we investigated whether Bcl-2 overexpression plays a role in the formation of newborn striatonigral projection neurons in the adult rat brain after transient middle cerebral artery occlusion (MCAO). Methods We infused human Bcl-2-expressing plasmid...

article

Coupled 3D discrete-continuum numerical modeling of pile penetration in sand

Jian Zhou, Qi-wei Jian, Jiao Zhang, Jian-jun Guo

Journal of Zhejiang University-SCIENCE A > 2012 > 13 > 1 > 44-55

A coupled discrete-continuum simulation incorporating a 3D aspect and non-circular particles was performed to analyze soil-pile interactions during pile penetration in sand. A self-developed non-circular particle numerical simulation program was used which considered sand near the pile as interacted particles using a discrete element method; the sand away from the pile was simulated as a continuous...

article

Ab initio study of AunIr (n=1–8) clusters

Ji-Xian Yang, Jian-Jun Guo, Dong Die

Computational and Theoretical Chemistry > 2011 > 963 > 2-3 > 435-438

The density functional method PW91P86 with relativistic effective core potentials (RECP) and LANL2DZ basis set have been used to investigate the possible stable geometrical configurations and relative stabilities of the lowest-lying isomers of iridium-doped gold clusters, Au _n Ir (n=1–8). Several low-lying isomers were determined. The results indicate that the ground-state Au _n Ir,...

chapter

Experimental research for phase DFIFT in the quantum communication system based on double M-Z interferometers

Bang-hong Guo, Jian-jun Guo, Guang-ming Cheng

10th International Conference on Optical Communications and Networks (ICOCN 2011) > 1 - 2

10th International Conference on Optical Communications and Networks (ICOCN 2011)

We present initially a novel real-time phase tracking method for drift phase, which is described by single-photon counts, and introduce an active compensating way for the periodic phase drift.

article

A gain-flatness optimization solution for feedback technology of wideband low noise amplifiers

Zhen-hua Li, Bang-hong Guo, Zheng-jun Wei, Song-hao Liu, more

Frontiers of Information Technology & Electronic Engineering > 2011 > 12 > 7 > 608-613

The S parameter expression of high-frequency models of the high electron mobility transistors (HEMTs) with basic feedback structure, especially the transmission gain S ₂₁, is presented and analyzed. In addition, an improved feedback structure and its theory are proposed and demonstrated, in order to obtain a better gain-flatness through the mutual interaction between the series inductor and the parallel...

article

Density functional study of AunRh (n=1–8) clusters

Ji-Xian Yang, Cheng-Fu Wei, Jian-Jun Guo

Physica B: Physics of Condensed Matter > 2010 > 405 > 23 > 4892-4896

The density functional method PW91P86 with relativistic effective core potentials (RECPs) and LANL2DZ basis set has been used to investigate the possible stable geometrical configurations and relative stabilities of the lowest-lying isomers of rhodium-doped gold clusters, Au _n Rh (n=1–8). Several low-lying isomers were determined. The results indicate that the ground-state Au _n Rh,...

article

Geometries, stabilities, and magnetic properties of Cr@Aun (n=1–8) clusters: Density functional theory study

Die Dong, Xiao-Yu Kuang, Jian-Jun Guo, Ben-Xia Zheng

Physica A: Statistical Mechanics and its Applications > 2010 > 389 > 22 > 5216-5222

The geometries, stabilities, and magnetic properties of Cr@Au _n (n=1–8) clusters have been studied by means of a density functional method PW91P86 and a LanL2DZ basis set. It is found that the Cr atom in the lowest energy Cr@Au _n isomers tend to occupy the most highly coordinated position and the ground state configuration of the Cr@Au _n clusters favor a planar structure, except...

article

First-principle study of AunFe (n=1–7) clusters

Dong Die, Xiao-Yu Kuang, Jian-Jun Guo, Ben-Xia Zheng

Journal of Molecular Structure: THEOCHEM > 2009 > 902 > 1-3 > 54-58

The geometrical structures, relative stabilities, and magnetic moments of iron-doped gold clusters, Au _n Fe (n=1–7), have been investigated using density functional method B3LYP and LanL2DZ basis set. Many low-lying isomers of the Au _n Fe clusters are obtained along with their electronic states. The results show that the ground-state Au _n Fe isomers possess a linear structure...

article

Density functional study of AunNi− (n=1–5) cluster anions

Jian-Jun Guo, Ji-Xian Yang, Dong Die

Journal of Molecular Structure: THEOCHEM > 2009 > 896 > 1-3 > 1-5

Nickel-doped gold cluster anions, Au _n Ni ⁻ (n=1–5), were investigated using the density functional method B3LYP with relativistic effective core potentials (RECP) and LANL2DZ basis set. The possible stable geometrical configurations with their electronic states are determined, and many of them in electronic configurations with a high spin multiplicity. The stability trend of the anionic...

article

Effect of cilostazol on cerebral arteries in secondary prevention of ischemic stroke

Jian-Jun Guo, En Xu, Qing-Yuan Lin, Guo-Ling Zeng, more

Neuroscience Bulletin > 2009 > 25 > 6 > 383-390

Objective To compare the effects of cilostazol on cerebral arteries and cerebrovascular blood flow in secondary prevention of ischemic stroke, with those of aspirin. Methods Sixty-eight patients who had ischemic stroke during the recent 1–6 months were recruited and randomized into cilostazol or aspirin group. Cerebrovascular condition was assessed by magnetic resonance angiography (MRA) and transcranial...

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INFONA - science communication portal

Search results for: Jian-Jun Guo

Shear strength of sandstone–mudstone particle mixture from direct shear test

Ecological risk assessment of the Gannan Plateau, northeastern Tibetan Plateau

Risk Factors, Clinical Features and Prognosis for Subtypes of Ischemic Stroke in a Chinese Population

Pathogenic differences of the entomopathogenic fungus Isaria cateniannulata to the spider mite Tetranychus urticae (Trombidiformes: Tetranychidae) and its predator Euseius nicholsi (Mesostigmata: Phytoseiidae)

The potential of microRNAs as human prostate cancer biomarkers: A meta‐analysis of related studies

Characterization of PD-L1 expression in Chinese non-small cell lung cancer patients with PTEN expression as a means for tissue quality screening

An in-vitro cocktail assay for assessing compound-mediated inhibition of six major cytochrome P450 enzymes

Properties and paper sizing application of waterborne polyurethane emulsions synthesized with isophorone diisocyanate

Interleukin-1β and cyclic AMP mediate the invasion of sheared chondrosarcoma cells via a matrix metalloproteinase-1-dependent mechanism

New striatal neurons form projections to substantia nigra in adult rat brain after stroke

Bcl-2 enhances the formation of newborn striatal long-projection neurons in adult rat brain after a transient ischemic stroke

Coupled 3D discrete-continuum numerical modeling of pile penetration in sand

Ab initio study of AunIr (n=1–8) clusters

Experimental research for phase DFIFT in the quantum communication system based on double M-Z interferometers

A gain-flatness optimization solution for feedback technology of wideband low noise amplifiers

Density functional study of AunRh (n=1–8) clusters

Geometries, stabilities, and magnetic properties of Cr@Aun (n=1–8) clusters: Density functional theory study

First-principle study of AunFe (n=1–7) clusters

Density functional study of AunNi− (n=1–5) cluster anions

Effect of cilostazol on cerebral arteries in secondary prevention of ischemic stroke

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