Search results for: Dilip V. Jeste

Items from 1 to 20 out of 165 results

article

Impact of educational attainment on time to cognitive decline among marginalized older adults: Cohort study of 20,311 adults

Dylan J. Jester, Barton W. Palmer, Michael L. Thomas, Lauren L. Brown, more

Journal of the American Geriatrics Society > 71 > 9 > 2913 - 2923

Background The effect of years of education on the maintenance of healthy cognitive functioning may differ by race and ethnicity given historical and ongoing inequities in educational quality. Methods We examined 20,311 Black, Latinx, and White adults aged 51–100 from the Health and Retirement Study (2008–2016). Telephone Interview for Cognitive Status‐27 data was used to measure cognitive functioning...

article

Artificial Intelligence for Mental Health and Mental Illnesses: an Overview

Sarah Graham, Colin Depp, Ellen E. Lee, Camille Nebeker, more

Current Psychiatry Reports > 2019 > 21 > 11 > 1-18

Purpose of Review Artificial intelligence (AI) technology holds both great promise to transform mental healthcare and potential pitfalls. This article provides an overview of AI and current applications in healthcare, a review of recent original research on AI specific to mental health, and a discussion of how AI can supplement clinical practice while considering its current limitations, areas needing...

article

Yoga to prevent mobility limitations in older adults: feasibility of a randomized controlled trial

Erik J. Groessl, Meghan Maiya, Laura Schmalzl, David Wing, more

BMC Geriatrics > 2018 > 18 > 1 > 1-11

Background The loss of mobility during aging impacts independence and leads to further disability, morbidity, and reduced life expectancy. Our objective was to examine the feasibility and safety of conducting a randomized controlled trial of yoga for older adults at risk for mobility limitations. Methods Sedentary older adults (n = 46; age 60–89) were recruited and randomized to either yoga or a...

article

Grit and Ambition are Associated with Better Neurocognitive and Everyday Functioning Among Adults Living with HIV

Raeanne C. Moore, Mariam A. Hussain, Caitlin W-M Watson, Pariya L. Fazeli, more

AIDS and Behavior > 2018 > 22 > 10 > 3214-3225

Grit and ambition are psychological factors that may protect neurocognitive function among persons living with HIV (PLWH). We examined associations between grit, ambition, premorbid verbal intellectual function, and current neurocognitive and everyday functioning among PLWH and persons without HIV (HIV−). 120 PLWH and 94 HIV− adults completed the Grit Scale (includes total score and consistency of...

article

Positive Psychological Factors are Linked to Successful Cognitive Aging Among Older Persons Living with HIV/AIDS

David J. Moore, Pariya L. Fazeli, Raeanne C. Moore, Steven P. Woods, more

AIDS and Behavior > 2018 > 22 > 5 > 1551-1561

We aimed to characterize successful cognitive aging (SCA) among older HIV-infected (HIV+) and HIV-uninfected (HIV−) adults, and to determine associations with positive psychological factors and health-related quality of life (HRQoL). Ninety-nine HIV+ and 46 HIV− older adults (≥ 50 years) completed measures of neurocognition, positive psychological factors, and HRQoL. Using study-defined SCA criteria...

article

Abnormal levels of vascular endothelial biomarkers in schizophrenia

Tanya T. Nguyen, Sheena I. Dev, Guanqing Chen, Sharon C. Liou, more

European Archives of Psychiatry and Clinical Neuroscience > 2018 > 268 > 8 > 849-860

Schizophrenia is associated with chronic low-grade inflammation, which has been linked to increased vascular risk and rates of cardiovascular disease. Levels of vascular endothelial growth factor (VEGF), intercellular adhesion molecule-1 (ICAM-1), and vascular cell adhesion molecule-1 (VCAM-1) have been related to aging and neurodegeneration, but their role in schizophrenia remains uncertain. Using...

article

Editorial Comment: Is the Placebo Effect Actually Increasing Over Time?

Dilip V. Jeste, Ellen E. Lee

The American Journal of Geriatric Psychiatry > 2017 > 25 > 9 > 1009-1011

article

Use of Tablet Devices in the Management of Agitation Among Inpatients with Dementia: An Open-Label Study

Ipsit V. Vahia, Rujvi Kamat, Cheng Vang, Carolina Posada, more

The American Journal of Geriatric Psychiatry > 2017 > 25 > 8 > 860-864

To investigate the feasibility, safety, and utility of tablet devices as novel nonpharmacologic tools in managing older psychiatric inpatients with agitation and dementia.Thirty-six patients at a geriatric psychiatry inpatient unit were provided with tablets when agitated and used various apps on the tablet related to communication, games, music, web browser, and photography during their stay. Study...

article

Who Are the Seniors with Subjective but Not Objective Cognitive Impairment?

Dilip V. Jeste, Graham M.L. Eglit

The American Journal of Geriatric Psychiatry > 2017 > 25 > 5 > 498-499

article

Abnormalities in chemokine levels in schizophrenia and their clinical correlates

Suzi Hong, Ellen E. Lee, Averria Sirkin Martin, Benchawanna Soontornniyomkij, more

Schizophrenia Research > 2017 > 181 > C > 63-69

Chemokines are promising biomarkers of immune activation and inflammation, but evidence for chemokine abnormalities in schizophrenia and their relationship to clinical factors remains inconclusive. We aimed to understand chemokine-related diagnostic differences and clinical correlates using a comprehensive panel and studying a large, well-characterized sample of adults with and without schizophrenia...

article

Peripheral inflammation related to lower fMRI activation during a working memory task and resting functional connectivity among older adults: a preliminary study

Sheena I. Dev, Raeanne C. Moore, Benchawanna Soontornniyomkij, Cristian L. Achim, more

International Journal of Geriatric Psychiatry > 32 > 3 > 341 - 349

Objective Peripheral inflammation has been associated with adverse effects on cognition and brain structure in late life, a process called ‘inflammaging.’ Identifying biomarkers of preclinical cognitive decline is critical in the development of preventative therapies, and peripheral inflammation may be able to serve as an indicator of cognitive decline. However, little is known regarding the relationship...

article

Leukocyte telomere length: Effects of schizophrenia, age, and gender

Owen M. Wolkowitz, Dilip V. Jeste, Averria Sirkin Martin, Jue Lin, more

Journal of Psychiatric Research > 2017 > 85 > C > 42-48

Schizophrenia is linked with early medical comorbidity and mortality. These observations indicate possible “accelerated biological aging” in schizophrenia, although prior findings are mixed, and few such studies have examined the role of gender. One putative marker of biological aging is leukocyte telomere length (LTL), which typically shortens with age.We assessed LTL in phenotypically well characterized...

article

Inflammation in Schizophrenia: Cytokine Levels and Their Relationships to Demographic and Clinical Variables

Ellen E. Lee, Suzi Hong, Averria Sirkin Martin, Lisa T. Eyler, more

The American Journal of Geriatric Psychiatry > 2017 > 25 > 1 > 50-61

Inflammation may play a role in the accelerated physical aging reported in schizophrenia, though biomarker findings and associations with demographic and clinical factors are inconsistent.In a cross-sectional, case-control design, 95 outpatients with schizophrenia (mean age ± SD: 48.1 ± 10.2 years) and 95 demographically comparable healthy comparison subjects (HCs) (mean age ± SD: 48.1 ± 12.1 years)...

article

Age-Friendly Communities Initiative: Public Health Approach to Promoting Successful Aging

Dilip V. Jeste, Dan G. Blazer, Kathleen C. Buckwalter, Keri-Leigh K. Cassidy, more

The American Journal of Geriatric Psychiatry > 2016 > 24 > 12 > 1158-1170

Older adults consistently prefer aging in place, which requires a high level of community support and services that are currently lacking. With a rapidly aging population, the present infrastructure for healthcare will prove even more inadequate to meet seniors' physical and mental health needs. A paradigm shift away from the sole focus on delivery of interventions at an individual level to more prevention-focused,...

article

Mild Neurocognitive Disorder: A Model for Accelerated Biological Aging?

Dilip V. Jeste, Barton W. Palmer

The American Journal of Geriatric Psychiatry > 2016 > 24 > 11 > 987-988

article

Validation of the UCSD Performance-based Skills Assessment (UPSA) in Hispanics with and without schizophrenia

Brent T. Mausbach, Denisse Tiznado, Veronica Cardenas, Dilip V. Jeste, more

Psychiatry Research > 2016 > 244 > C > 388-393

The UCSD Performance-based Skills Assessment (UPSA) is a widely used measure of functional capacity with strong reliability and validity. However there is a lack of psychometric data on Hispanics. The purpose of this study was to determine the impact of acculturation and education on UPSA performance among 62 Hispanic participants with schizophrenia or schizoaffective disorder and 46 healthy comparison...

article

Response to Cohen and Germain: Defining a Good Death

Emily A. Meier, Jarred V. Gallegos, Lori P. Montross-Thomas, Colin A. Depp, more

The American Journal of Geriatric Psychiatry > 2016 > 24 > 10 > 942

article

Elevated plasma F2-isoprostane levels in schizophrenia

Ellen E. Lee, Lisa T. Eyler, Owen M. Wolkowitz, Averria Sirkin Martin, more

Schizophrenia Research > 2016 > 176 > 2-3 > 320-326

Schizophrenia is one of the most disabling psychiatric disorders with increased morbidity and mortality. Both schizophrenia and oxidative stress have been associated with accelerated aging. Previous studies found increased oxidative stress in individuals with schizophrenia, though only one study measured F2-isoprostanes and did so in urine. To our knowledge, the present study is the first to assess...

article

Peer Review at the American Journal of Geriatric Psychiatry—An Appeal to the Better Angels of Our Nature

Charles F. Reynolds, Dan G. Blazer, Gwenn Smith, Dilip V. Jeste

The American Journal of Geriatric Psychiatry > 2016 > 24 > 9 > 671-672

article

Defining a Good Death (Successful Dying): Literature Review and a Call for Research and Public Dialogue

Emily A. Meier, Jarred V. Gallegos, Lori P. Montross Thomas, Colin A. Depp, more

The American Journal of Geriatric Psychiatry > 2016 > 24 > 4 > 261-271

There is little agreement about what constitutes good death or successful dying. The authors conducted a literature search for published, English-language, peer-reviewed reports of qualitative and quantitative studies that provided a definition of a good death. Stakeholders in these articles included patients, prebereaved and bereaved family members, and healthcare providers (HCPs). Definitions found...

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INFONA - science communication portal

Search results for: Dilip V. Jeste

Impact of educational attainment on time to cognitive decline among marginalized older adults: Cohort study of 20,311 adults

Artificial Intelligence for Mental Health and Mental Illnesses: an Overview

Yoga to prevent mobility limitations in older adults: feasibility of a randomized controlled trial

Grit and Ambition are Associated with Better Neurocognitive and Everyday Functioning Among Adults Living with HIV

Positive Psychological Factors are Linked to Successful Cognitive Aging Among Older Persons Living with HIV/AIDS

Abnormal levels of vascular endothelial biomarkers in schizophrenia

Editorial Comment: Is the Placebo Effect Actually Increasing Over Time?

Use of Tablet Devices in the Management of Agitation Among Inpatients with Dementia: An Open-Label Study

Who Are the Seniors with Subjective but Not Objective Cognitive Impairment?

Abnormalities in chemokine levels in schizophrenia and their clinical correlates

Peripheral inflammation related to lower fMRI activation during a working memory task and resting functional connectivity among older adults: a preliminary study

Leukocyte telomere length: Effects of schizophrenia, age, and gender

Inflammation in Schizophrenia: Cytokine Levels and Their Relationships to Demographic and Clinical Variables

Age-Friendly Communities Initiative: Public Health Approach to Promoting Successful Aging

Mild Neurocognitive Disorder: A Model for Accelerated Biological Aging?

Validation of the UCSD Performance-based Skills Assessment (UPSA) in Hispanics with and without schizophrenia

Response to Cohen and Germain: Defining a Good Death

Elevated plasma F2-isoprostane levels in schizophrenia

Peer Review at the American Journal of Geriatric Psychiatry—An Appeal to the Better Angels of Our Nature

Defining a Good Death (Successful Dying): Literature Review and a Call for Research and Public Dialogue

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