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Various antigen structures initiate the classical and the lectin pathways of complement activation. Multidomain modular proteases (C1r, C1s and MASPs) are involved in the initiation complexes of both pathways. Despite the identical domain organization of these serine proteases there are differences in their specificities and functions. A comparative analysis is given on the similarities and differences...
Various antigen structures initiate the classical and the lectin pathways of complement activation. Multidomain modular proteases (C1r, C1s and MASPs) are involved in the initiation complexes of both pathways. Despite the identical domain organization of these serine proteases there are differences in their specificities and functions. A comparative analysis is given on the similarities and differences...
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