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Vitellogenins (Vtgs) are yolk precursor proteins in oviparous species and are cleaved into three portions–lipovitellin I (LVI), phosvitin (PV), and lipovitellin II (LVII)–in oocytes in vertebrates. In the present study, we found that the zebrafish genome contains at least seven vtg genes (vtg1–7) encoding heterogeneous vitellogenins with three distinct types of Vtgs: type I (Vtg1, 4–7) contains all...
Many basic helix-loop-helix transcriptional factors play important roles in vertebrate neurogenesis. Among them, Neurogenins act as determination factors and initiate the expression of differentiation genes such as neuroD and other neurogenic genes. Here we describe a zebrafish cDNA (neurogenin3 or ngn3) encoding a novel member of the Neurogenin family closest to mouse Ngn3 and human NGN3. Using a...
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