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The present study was carried out to examine the chemopreventive effects of thiacremonone, which is found in heated garlic, on the formation of the preneoplastic foci and glutathione-dependent detoxifying enzyme activities in rat hepatocarcinogenesis. F344 rats were given an intraperitoneal injection of N-nitrosodiethylamine (DEN) at a dose of 200 mg/kg body weight and were then administered a gavage...
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