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Recent studies suggest that SIPA1 encoding a Rap GTPase‐activating protein SPA‐1 is a candidate metastasis efficiency‐modifying gene in human breast cancer. In this study, we investigated the expression and function of SPA‐1 in human prostate cancer (CaP). Immunohistochemical studies of tumor specimens from CaP patients revealed a positive correlation of SPA‐1 expression with disease progression and...
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