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Monocentric cohorts suggested that radiation-induced CD8 T-lymphocyte apoptosis (RILA) can predict late toxicity after curative intent radiotherapy (RT). We assessed the role of RILA as a predictor of breast fibrosis (bf+) after adjuvant breast RT in a prospective multicenter trial.A total of 502 breast-cancer patients (pts) treated by conservative surgery and adjuvant RT were recruited at ten centers...
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