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Background The activation of phototransduction cascade in rod photoreceptors has been well studied in literature, but there is a lack of a mature kinetic model structure covering both the activation and inactivation processes. Methods In this work, a kinetic model structure is developed to describe the major activation and inactivation processes in vertebrate rod photoreceptors with the electroretinogram...
The molecular mechanisms of phototransduction in the rod photorecptor cell have been reasonably well established but have not been represented in the form of a system model. In this work, we formulated a basic system model structure by representing the major biochemical reactions in the phototransduction cascade as a seventh-order system of kinetic equations with the ERG a-wave as a measurable output...
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