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The proliferation and differentiation of skeletal muscle satellite cells is regulated by multiple regulatory factors including non-coding RNAs. It has been reported that miR-133b regulates myogenesis. In this study, we detected a novel lncRNA, lnc133b, which is completely complemented by mature miR-133b, indicating that lnc133b may regulate the expression of miR-133b by “sponge” miR-133b. A luciferase...
The low success rate of somatic cell nuclear transfer (SCNT) is primarily due to incomplete reprogramming of the transferred nuclei. As an inhibitor of histone deacetylase, trichostatin A (TSA) might promote the reprogramming process and improve cloned embryo development. In the current study, TSA was investigated in terms of its ability to improve the development of cloned goat embryos, and the appropriate...
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