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Cancer stem cells (CSCs), a type of cell with self‐renewal, unlimited proliferation, and insensitivity to common physical and chemical factors, are the key to cancer metastasis, recurrence, and chemo‐resistance. Available CSCs inhibition strategies are mainly based on small molecule drugs, yet are limited by their off‐target toxicity. The link between CSCs and non‐CSCs interconversion is difficult...
Palladium nanosheets (Pd NSs) are well‐investigated photothermal therapy agents, but their catalytic potential for tumor therapy has been underexplored owing to the inactive dominant (111) facets. Herein, lattice tensile strain is introduced by surface reconstruction to activate the inert surface, endowing the strained Pd NSs (SPd NSs) with photodynamic, catalase‐like, and peroxidase‐like properties...
Dual phototherapy, including photodynamic therapy (PDT) and photothermal therapy (PTT), has shown a great prospect in cancer treatment. However, its therapeutic effect is restricted by the depth of light penetration in tissue and tumor hypoxia environment. Herein, inspired by the specific response of nanozymes to the tumor microenvironment (TME), a simple and versatile nanozyme‐mediated synergistic...
A photoresponsive nanozyme with peroxidase‐ and catalase‐like activities, photodynamic and photothermal properties is designed in article number 2007090 by Huiyu Liu and co‐workers. Its synergistic catalytic therapy and dual phototherapy show unique advantages for tumor treatment.
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