Search results for: Wei Chen

Items from 1 to 20 out of 10,144 results

article

The protective effect of EGF‐activated ROS in human corneal epithelial cells by inducing mitochondrial autophagy via activation TRPM2

Yanan Huo, Wei Chen, Xiaoxiao Zheng, Jinchuan Zhao, more

Journal of Cellular Physiology > 235 > 10 > 7018 - 7029

Oxidative stress is a major pathogenesis of some ocular surface diseases. Our previous study demonstrated that epidermal growth factor (EGF)‐activated reactive oxygen species (ROS) could protect against human corneal epithelial cell (HCE) injury. In the present study, we aimed to explore the role and mechanisms of oxidative stress and mitochondrial autophagy in HCE cells subjected to scratch injury...

article

Integrative genomic analyses identify WDR12 as a novel oncogene involved in glioblastoma

Jun‐Liang Li, Cheng Chen, Wei Chen, Ling‐Feng Zhao, more

Journal of Cellular Physiology > 235 > 10 > 7344 - 7355

Glioblastoma (GBM) is the most malignant primary brain tumor in adults. Due to its invasive nature, it cannot be thoroughly eliminated. WD repeat domain 12 (WDR12) processes the 32S precursor rRNA but cannot affect the synthesis of the 45S/47S primary transcript. In this study, we found that WDR12 is highly expressed in GBM according to the analysis results of mRNA expression by The Cancer Genome...

article

Theoretical study of propylene epoxidation heterogeneous‐homogeneous mechanism over MoO_x/SiO₂ catalyst

Zhehong Wan, Zenan Lin, Jiahui Peng, Wei Chen, more

International Journal of Quantum Chemistry > 120 > 18 > n/a - n/a

The green direct propylene (C₃H₆) epoxidation on MoO_x is well studied by experimental methods, but detailed molecular reaction mechanism studies using in‐silico experiments method are few. Here, the different oxidation heterogeneous‐homogeneous pathways for MoO_x/SiO₂ catalyst are calculated, mainly involving Mo=O on di‐oxo tetracoordinate MoO_x, allyl peroxy (C₃H₅OO•), and allyloxy (C₃H₅O•) radicals...

article

Tumor necrosis factor‐alpha blockade ameliorates inflammatory response in two children with chronic infantile neurological, cutaneous and articular syndrome

Xiao‐yan Luo, An‐wei Chen, Jin‐hua Cai, Jin Fang, more

The Journal of Dermatology > 47 > 8 > 903 - 906

Chronic infantile neurological, cutaneous and articular (CINCA) syndrome is a rare autoinflammatory disease caused by monogenic defects in the NLRP3 gene. Pro‐inflammatory cytokines such as interleukin (IL)‐1β play a crucial role in the pathogenesis, and IL‐1 receptor antagonists have been regarded as the mainstay therapy. Endogenous tumor necrosis factor (TNF)‐α was found recently to be involved...

article

Effects of Ga and Sn on the electrochemical behavior of Mg–6Al–1Zn as anode materials

Xiaofeng Wan, Wei Chen, Jingling Zhou, Hua Zhang, more

Materials and Corrosion > 71 > 8 > 1339 - 1345

The microstructure and electrochemical behavior of Mg–6Al–1Zn, Mg–6Al–1Zn–1Ga, Mg–6Al–1Zn–1Sn, and Mg–6Al–1Zn–0.5Sn–0.5Ga as anode materials in a 3.5 wt% NaCl solution are compared systematically. The results show that Sn alloying refines the second‐phases of Mg–6Zn–1Al by promoting tiny granular Mg₁₇Al₁₂ phases containing Sn, and inspires their disperse distribution. However, the Ga results in the...

article

Digital Workflow for Implant Rehabilitation with Double Full‐Arch Monolithic Zirconia Prostheses

Panos Papaspyridakos, Konstantinos Chochlidakis, Kiho Kang, Yo‐wei Chen, more

Journal of Prosthodontics > 29 > 6 > 460 - 465

The purpose of the present report is to illustrate a proof‐of‐concept protocol with the double digital scanning (DDS) technique for complete digital workflow in double full‐arch implant rehabilitation. Two patients (4 restored arches) presented with hopeless dentitions and they were treated with a 4‐appointment prosthodontic protocol and monolithic zirconia prostheses implementing a complete digital...

article

Simultaneous determination of seven compounds in Chinese patent medicines Chenxiangqu by matrix solid‐phase dispersion coupled with ultra high performance liquid chromatography and quadrupole time‐of‐flight mass spectrometry

Chu Chu, Huan Zhang, Hui Mao, Caijing Liu, more

Journal of Separation Science > 43 > 14 > 2869 - 2879

A simple, efficient, and sensitive strategy by coupling matrix solid‐phase dispersion with ultra high performance liquid chromatography quadrupole time‐of‐flight mass spectrometry was proposed to extract and determine three types of components (including seven analytes) in Chinese patent medicines Chenxiangqu. The highly ordered mesoporous material Fe‐SBA‐15 synthesized under weakly acidic conditions...

article

Recombinant Adenosine Deaminase Ameliorates Inflammation, Vascular Disease, and Fibrosis in Preclinical Models of Systemic Sclerosis

Yun Zhang, Honglin Zhu, Florian Layritz, Hui Luo, more

Arthritis & Rheumatology > 72 > 8 > 1385 - 1395

Objective Systemic sclerosis (SSc) is characterized by fibrosis, vascular disease, and inflammation. Adenosine signaling plays a central role in fibroblast activation. We undertook this study to evaluate the therapeutic effects of adenosine depletion with PEGylated adenosine deaminase (PEG‐ADA) in preclinical models of SSc. Methods The effects of PEG‐ADA on inflammation, vascular remodeling, and...

article

Preparing for COVID‐19: The experiences of a long‐term care facility in Taiwan

Cheng‐Ren Chen, Hui‐Chun Huang, Hsiu‐Chen Huang, Wei Chen

Geriatrics & Gerontology International > 20 > 7 > 734 - 735

article

Proteomic analysis of “Oriental Beauty” oolong tea leaves with different degrees of leafhopper infestation

Han‐Ju Chien, Man‐Miao Yang, Wei‐Chen Wang, Xiang‐Gui Hong, more

Rapid Communications in Mass Spectrometry > 34 > 15 > n/a - n/a

Rationale Oriental Beauty, a type of oolong tea native to Taiwan, is highly prized by connoisseurs for its unique fruity aroma and sweet taste. Leaves of Oriental Beauty vary in appearance, aroma, and taste, depending on the degree of tea green leafhopper (Jacobiasca formosana) infestation. In this study, the aim is to investigate the differential expression of proteins in leaves with low, medium,...

article

Effect of pitaya peel powder addition on the phytochemical and textural properties and sensory acceptability of dried and cooked noodles

Sy‐Yu Shiau, Guan‐Hua Li, Wei‐Chen Pan, Cen Xiong

Journal of Food Processing and Preservation > 44 > 7 > n/a - n/a

Pitaya peel, a by‐product during processing, contains many phytochemicals. To make good use of it, an approach of adding pitaya peel powder (PPP) to noodle as a bioactive ingredient was applied. The objective of this study was to investigate the effect of PPP level (0%‐9%) on phytochemical, textural, and sensory properties of noodle. With an increase in the PPP level, 2, 2‐diphenyl‐1‐picrylhydrazyl...

article

Doping Dependent In‐Plane and Cross‐Plane Thermoelectric Performance of Thin n‐Type Polymer P(NDI2OD‐T2) Films

Regina M. Kluge, Nitin Saxena, Wei Chen, Volker Körstgens, more

Advanced Functional Materials > 30 > 28 > n/a - n/a

Thermoelectric generators pose a promising approach in renewable energies as they can convert waste heat into electricity. In order to build high efficiency devices, suitable thermoelectric materials, both n‐ and p‐type, are needed. Here, the n‐type high‐mobility polymer poly[N,N′‐bis(2‐octyldodecyl)naphthalene‐1,4,5,8‐bis(dicarboximide)‐2,6‐diyl]‐alt‐5,5′‐(2,2′‐bithiophene) (P(NDI2OD‐T2)) is focused...

article

Thermoelectric Polymers: Doping Dependent In‐Plane and Cross‐Plane Thermoelectric Performance of Thin n‐Type Polymer P(NDI2OD‐T2) Films (Adv. Funct. Mater. 28/2020)

Regina M. Kluge, Nitin Saxena, Wei Chen, Volker Körstgens, more

Advanced Functional Materials > 30 > 28 > n/a - n/a

Thermoelectric devices based on conducting polymers have gained much attention in recent years regarding harvesting of waste heat energy by applying a temperature gradient along the material. In article number 2003092, Peter Müller‐Buschbaum and co‐workers focus on solution doping of an n‐type high‐mobility polymer and explain the discrepancy in thermoelectric performance depending on the charge carriers...

article

Asclepius and Yellow Ribbon techniques: Efficacious alternative strategies for advancing a coronary sinus electrophysiology catheter

Tse‐Wei Chen, Mu‐Shiang Huang, Wei‐Da Lu, Yu‐Hao Wu, more

Annals of Noninvasive Electrocardiology > 25 > 4 > n/a - n/a

Background Inserting an electrophysiological (EP) catheter into the coronary sinus (CS) via the femoral vein can be difficult and time‐consuming in patients with variants of the CS orifice or lumen curve. Our experience with such patients inspired us to develop two new techniques: the Asclepius and Yellow Ribbon techniques. Methods Data from a 4‐year period were retrieved from records of patients...

article

Ginsenoside 20(S)‐Rg3 upregulates HIF‐1α‐targeting miR‐519a‐5p to inhibit the Warburg effect in ovarian cancer cells

Jiaojiao Lu, Hong Chen, Fang He, Yuanyi You, more

Clinical and Experimental Pharmacology and Physiology > 47 > 8 > 1455 - 1463

The Warburg effect, one of the metabolic hallmarks of cancer, is responsible for rapid energy production through a high rate of aerobic glycolysis. Ginsenoside 20(S)‐Rg3 antagonizes the Warburg effect in ovarian cancer cells by upregulating some microRNAs, including miR‐519a‐5p, that target key enzymes involved in aerobic glycolysis. How 20(S)‐Rg3‐upregulated miR‐519a‐5p influences the Warburg effect...

article

Metabolomics analysis and metabolite‐agronomic trait associations using kernels of wheat (Triticum aestivum) recombinant inbred lines

Taotao Shi, Anting Zhu, Jingqi Jia, Xin Hu, more

The Plant Journal > 103 > 1 > 279 - 292

Plants produce numerous metabolites that are important for their development and growth. However, the genetic architecture of the wheat metabolome has not been well studied. Here, utilizing a high‐density genetic map, we conducted a comprehensive metabolome study via widely targeted LC‐MS/MS to analyze the wheat kernel metabolism. We further combined agronomic traits and dissected the genetic relationship...

article

A Novel Method of Simultaneous In Situ Decompression of Lateral Calcaneal Bulge and Subtalar Arthrodesis Via a Single Incision for Malunion After Calcaneal Fractures

Tao Zhang, Wei Chen, Guangrong Yu, Xuebin Zhang, more

Orthopaedic Surgery > 12 > 3 > 827 - 835

Objective The aim of this study was to introduce a novel method of simultaneous in situ decompression of lateral calcaneal bulge and subtalar arthrodesis via a single incision for malunion after calcaneal fractures and evaluate the feasibility of this method. Methods From September 2010 to October 2011, six patients (five males and one female) with malunion and delayed heel pain after conservative...

article

Biomechanical Study on the Stress Distribution of the Knee Joint After Tibial Fracture Malunion with Residual Varus–Valgus Deformity

Ming Li, Hengrui Chang, Ning Wei, Wenli Chang, more

Orthopaedic Surgery > 12 > 3 > 983 - 989

Objective To investigate the effect of residual varus and valgus deformity on the stress distribution of the knee joint after tibial fracture malunion. Methods Fourteen adult cadaver specimens were selected to establish the models of tibial fractures, which were fixed subsequently at neutral position (anatomical reduction) and malunion positions (at 5°, 10°, and 15° valgus positions, and 5°, 10°,...

article

Development of a Novel Multiparametric MRI Radiomic Nomogram for Preoperative Evaluation of Early Recurrence in Resectable Pancreatic Cancer

Tian‐Yu Tang, Xiang Li, Qi Zhang, Cheng‐Xiang Guo, more

Journal of Magnetic Resonance Imaging > 52 > 1 > 231 - 245

Background In pancreatic cancer, methods to predict early recurrence (ER) and identify patients at increased risk of relapse are urgently required. Purpose To develop a radiomic nomogram based on MR radiomics to stratify patients preoperatively and potentially improve clinical practice. Study Type Retrospective. Population We enrolled 303 patients from two medical centers. Patients with a disease‐free...

article

Corrigendum: Characterization of Meiothermus taiwanensis Galactokinase and its Use in the One‐Pot Enzymatic Synthesis of Uridine Diphosphate‐Galactose and the Chemoenzymatic Synthesis of the Carbohydrate Antigen Stage Specific Embryonic Antigen‐3

Si‐Peng Li, Wei‐Chen Hsiao, Ching‐Ching Yu, Wei‐Ting Chien, more

Advanced Synthesis & Catalysis > 362 > 12 > 2547 - 2547

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INFONA - science communication portal

Search results for: Wei Chen

The protective effect of EGF‐activated ROS in human corneal epithelial cells by inducing mitochondrial autophagy via activation TRPM2

Integrative genomic analyses identify WDR12 as a novel oncogene involved in glioblastoma

Theoretical study of propylene epoxidation heterogeneous‐homogeneous mechanism over MoO_x/SiO₂ catalyst

Tumor necrosis factor‐alpha blockade ameliorates inflammatory response in two children with chronic infantile neurological, cutaneous and articular syndrome

Effects of Ga and Sn on the electrochemical behavior of Mg–6Al–1Zn as anode materials

Digital Workflow for Implant Rehabilitation with Double Full‐Arch Monolithic Zirconia Prostheses

Simultaneous determination of seven compounds in Chinese patent medicines Chenxiangqu by matrix solid‐phase dispersion coupled with ultra high performance liquid chromatography and quadrupole time‐of‐flight mass spectrometry

Recombinant Adenosine Deaminase Ameliorates Inflammation, Vascular Disease, and Fibrosis in Preclinical Models of Systemic Sclerosis

Preparing for COVID‐19: The experiences of a long‐term care facility in Taiwan

Proteomic analysis of “Oriental Beauty” oolong tea leaves with different degrees of leafhopper infestation

Effect of pitaya peel powder addition on the phytochemical and textural properties and sensory acceptability of dried and cooked noodles

Doping Dependent In‐Plane and Cross‐Plane Thermoelectric Performance of Thin n‐Type Polymer P(NDI2OD‐T2) Films

Thermoelectric Polymers: Doping Dependent In‐Plane and Cross‐Plane Thermoelectric Performance of Thin n‐Type Polymer P(NDI2OD‐T2) Films (Adv. Funct. Mater. 28/2020)

Asclepius and Yellow Ribbon techniques: Efficacious alternative strategies for advancing a coronary sinus electrophysiology catheter

Ginsenoside 20(S)‐Rg3 upregulates HIF‐1α‐targeting miR‐519a‐5p to inhibit the Warburg effect in ovarian cancer cells

Metabolomics analysis and metabolite‐agronomic trait associations using kernels of wheat (Triticum aestivum) recombinant inbred lines

A Novel Method of Simultaneous In Situ Decompression of Lateral Calcaneal Bulge and Subtalar Arthrodesis Via a Single Incision for Malunion After Calcaneal Fractures

Biomechanical Study on the Stress Distribution of the Knee Joint After Tibial Fracture Malunion with Residual Varus–Valgus Deformity

Development of a Novel Multiparametric MRI Radiomic Nomogram for Preoperative Evaluation of Early Recurrence in Resectable Pancreatic Cancer

Corrigendum: Characterization of Meiothermus taiwanensis Galactokinase and its Use in the One‐Pot Enzymatic Synthesis of Uridine Diphosphate‐Galactose and the Chemoenzymatic Synthesis of the Carbohydrate Antigen Stage Specific Embryonic Antigen‐3

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