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Dopamine causes inhibition of Na + ,K + -ATPase activity via activation of dopamine D 1 -like receptors. It is the phosphorylation of Serine 18 of the α 1 -subunit of Na + ,K + -ATPase which results in the inhibition of the enzyme activity; however, such a phosphorylation by dopamine D 1 -like receptor agonist has not been demonstrated...
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