The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
Background information
Poly(ADP‐ribose) Polymerase‐1 (PARP‐1) is predominantly a nuclear protein and involved in various cellular processes like DNA repair, cell death, development, chromatin modulation etc. PARP‐1 utilizes NAD+ and adds negatively charged PAR moieties on the target proteins. Over‐activation of PARP‐1 has been shown to cause energy crisis mediated cell death in which mitochondrial...
Background information
Poly(ADP‐ribose) polymerase‐1 (PARP‐1) has been attributed to varied roles in DNA repair, cell cycle, cell death, etc. Our previous reports demonstrate the role of PARP‐1 during Dictyostelium discoideum development by its constitutive downregulation as well as by PARP‐1 ortholog, ADP ribosyl transferase 1 A (ADPRT1A) overexpression. The current study analyses and strengthens...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.