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Graphene (GR) can strongly interact with aptamers due to hydrophobic and π–π stacking interactions between nucleotide bases and GR, but hardly interact with aptamer–target complexes or rigid double-stranded DNA. The unique GR/aptamers interaction has been fascinatingly developed in fluorescent assay, colorimetric biosensing and mass spectrometric analysis. However, exploration of the unique GR/aptamers...
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