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Transient blood-brain barrier (BBB) opening via focused ultrasound (FUS) combined with intravenously circulating microbubbles (MBs) may have a role in the treatment of Alzheimer's disease (AD). Spectral characteristics of MB emissions recorded during the procedures using single-element detectors have correlated with biological outcomes [McDannold et al. PMB 2006], leading to the development of acoustic...
Advances in medical imaging have enabled the development of new minimally and completely noninvasive therapies that produce a desired biological effect in a target, such as a tumor, with minimal damage to the surrounding tissue. One means of noninvasively achieving bioeffects in tissue is the use of ultrasound to generate heat.
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