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Second-site revertants were selected from a respiratory-deficient mutant carrying the mutation D369N located in a loop between helices IX and X close to H376 and H378, the proposed ligands of haem a 3 and haem a, respectively. A reversion was observed in subunit II, in the vicinity of the Cu A ligands. This same reversion compensates the subunit I deficiency mutation, S140L, assumed...
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