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Background Docetaxel (DTX) is an anticancer drug that is currently formulated with polysorbate 80 and ethanol (50:50, v/v) in clinical use. Unfortunately, this formulation causes hypersensitivity reactions, leading to severe side-effects, which have been primarily attributed to polysorbate 80. Methods In this study, a DTX-loaded human serum albumin (HSA) nanoparticle (DTX-NP) was designed to overcome...
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