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Guaiazulene and related derivatives were famous for diverse biological activities. In an effort to discover new highly efficient candidate drugs derived from guaiazulene, four series of guaiazulene derivatives were designed, synthesized, and evaluated for antiproliferation, antiviral, anti‐inflammatory and peroxisome proliferators‐activated receptor γ (PPARγ) signalling pathway agonist activities...
Seven new kalihinene diterpenoids, kalihioxepanes A—G (1—7) bearing a rare oxepane ring, were isolated from sponge Acanthella cavernosa collected from the South China Sea. The structures and absolute configurations were elucidated by comprehensive spectroscopic analysis, single crystal X‐ray diffraction, and quantum chemical calculation methods. Kalihioxepane A (1) displayed strong cytotoxicity against...
Ten new 9,11-secosteroids, subergorgols A–J (1–10), including two pairs of epimers (3/4, and 6/7), along with three known analogues (11–13) were isolated from the South China Sea gorgonian Subergorgia suberosa. The structures of these compounds were elucidated on the basis of extensive spectroscopic analyses and comparison with the literature data. The cytotoxicities in vitro against three selected...
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