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Macrophages or activated microglia in the subretinal space are considered a hallmark of some retinal pathologies. We investigated the effects of age, pigmentation and CX 3 CR1 deficiency on the accumulation of macrophages/activated microglia in the outer retina of young and old Cx 3 cr1 gfp/gfp (CX 3 CR1-deficient) or Cx 3 cr1 gfp/+ mice on either a...