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Heart Valve Leaflets
In article number 2307106, Sangmin Lee, Se Yong Jung, Jinkee Hong, and co‐workers present a silk fibroin‐based heart valve leaflet. Notably, it exhibits a hierarchical structure physically optimal for replacing the natural heart valve leaflet. An aortic valve composed of silk fibroin‐based leaflets shows an excellent valve performance, demonstrating its potential as a cost‐effective...
Bioprosthetic valves are employed to replace defective heart valves. However, structural degeneration is prevalent in bioprosthetic valves because the heart valve leaflets are exposed to extreme and repetitive cardiovascular pressure. Herein, a silk fibroin‐based heart valve leaflet, which executes the physiological role of a heart valve, is developed. To this end, a templated assembly technology...