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In order to evaluate the role of metallothionein (MT)-III in cadmium (Cd)-induced testicular toxicity, we examined the sensitivity of MT-III null mice to severe testicular injury caused by Cd.Male MT-III null mice, MT-I/II null mice and wild-type mice were given a subcutaneous injection of CdCl 2 (15μmol/kg). The testis was collected from each mouse at 6, 12 and 24h after Cd administration...
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