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BackgroundDespite the availability of effective treatments for depression, many patients under the care of primary care physicians do not achieve remission. Clinical Outcomes in Measurement‐based Treatment (COMET) was designed to assess whether communicating patient‐reported depression symptom severity to primary care physicians affects patient outcomes at 6 months.
MethodsNine hundred fifteen patients (intervention: n = 503; control: n = 412) diagnosed with major depressive disorder were enrolled in a prospective trial in which physician practice sites were assigned to either the intervention or control study arm. Only patients who were prescribed an antidepressant by their physician were eligible, but medication type was independent of the study protocol. Intervention‐arm physicians received monthly updates on their patients’ depression severity, which was determined with the nine‐item Patient Health Questionnaire (PHQ‐9) administered during telephone interviews. Remission was defined as a PHQ‐9 score <5 at 6 months; response was defined as a score reduction ≥50%...
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