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We investigated the usefulness of cerebrospinal fluid (CSF) β-amyloid42 (Aβ42), β-amyloid40 (Aβ40) and tau analyses in the diagnosis of Alzheimer's disease (AD). The study included 41 definite AD cases, 80 patients with probable AD, 27 with other dementias and 39 neurological controls. Aβ42, Aβ40 and tau protein concentrations in CSF were measured of using ELISA assays. Aβ42 levels were decreased...
We investigated the effect of apolipoprotein E (apoE) genotype on amyloid load in the frontal and cerebellar cortices of 24 patients with definite Alzheimer disease (AD) and 19 controls. Amyloid load was examined by using two methods: 1) acid-extractable amyloid beta-protein (Aβ) and insoluble Aβ levels of frontal and cerebellar cortices were measured by using enzyme-linked immunosorbent assay, and...
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