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Abstract. Human seminal plasma spontaneously coagulates after ejaculation. The major component of this coagulum is semenogelin I, a 52-kDa protein expressed exclusively in the seminal vesicles. Recently, a sperm motility inhibitor has been found to be identical to semenogelin I, suggesting that it may also be a physiological sperm motility inhibitor. The protein is rapidly cleaved after ejaculation...
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