Search results for: Klaus Tiemann

Items from 1 to 20 out of 53 results

article

Imaging in CHD—who runs the show: Editorial to “congenital anatomy, acquired pathology—a synergistic approach to echocardiographic evaluation of the adult with congenital heart disease”

Elio Caruso, Klaus Tiemann

Echocardiography > 40 > 3 > 156 - 157

article

ECHOCARDIOGRAPHY: A Journal of Cardiovascular Imaging and Intervention

Ralph Stephan von Bardeleben, Klaus Tiemann

Echocardiography > 39 > 1 > 4 - 4

chapter

A planning system of the implant size and position for minimally-invasive closure of the left atrial appendage

Eva C. Graf, Klaus Tiemann, Julian Praceus, Tim C. Lueth

2016 6th IEEE International Conference on Biomedical Robotics and Biomechatronics (BioRob) > 293 - 298

2016 6th IEEE International Conference on Biomedical Robotics and Biomechatronics (BioRob)

This article describes a planning program and process for the implant size and position planning for the minimally-invasive closure of the left atrial appendage. To prevent strokes in patients suffering from atrial fibrillation an implant that occludes the orifice of the left atrial appendage can be inserted into the heart through a catheter. A critical step during the procedure is the correct choice...

chapter

Histogram-Based Optical Flow for Functional Imaging in Echocardiography

Sönke Schmid, Daniel Tenbrinck, Xiaoyi Jiang, Klaus Schäfers, more

Lecture Notes in Computer Science > Computer Analysis of Images and Patterns > Medical Imaging > 477-485

Echocardiographic imaging provides various challenges for medical image analysis due to the impact of physical effects in the process of data acquisition. The most significant difference to other medical data is its high level of speckle noise that makes the use of conventional algorithms difficult. Motion analysis on ultrasound (US) data is often referred to as ’Speckle Tracking’ which plays an important...

chapter

Imaging in Cardiovascular Research

Michael Schäfers, Klaus Tiemann, Michael Kuhlmann, Lars Stegger, more

Small Animal Imaging > Special Applications > 449-471

Despite enormous investment into cardiovascular research on all levels worldwide, cardiovascular events such as myocardial infarction, heart failure, tachyarrhythmia or stroke remain the major causes for death and inability in all developed countries. Conventional clinical cardiovascular imaging nowadays provides high-resolution visualization of the morphology of vessels and the myocardium. To translate...

article

Soluble Flt-1 links microvascular disease with heart failure in CKD

Giovana S. Di Marco, Dominik Kentrup, Stefan Reuter, Anna B. Mayer, more

Basic Research in Cardiology > 2015 > 110 > 3 > 1-14

Chronic kidney disease (CKD) is associated with an increased risk of heart failure (HF). Elevated plasma concentrations of soluble Flt-1 (sFlt-1) have been linked to cardiovascular disease in CKD patients, but whether sFlt-1 contributes to HF in CKD is still unknown. To provide evidence that concludes a pathophysiological role of sFlt-1 in CKD-associated HF, we measured plasma sFlt-1 concentrations...

article

Ultrasound-mediated gene delivery of naked plasmid DNA in skeletal muscles: A case for bolus injections

Pedro Gomes Sanches, Mareike Mühlmeister, Ralf Seip, Eric Kaijzel, more

Journal of Controlled Release > 2014 > 195 > C > 130-137

Localized gene delivery has many potential clinical applications. However, the nucleic acids (e.g. pDNA and siRNA) are incapable of passively crossing the endothelium, cell membranes and other biological barriers which must be crossed to reach their intracellular targets. A possible solution is the use of ultrasound to burst circulating microbubbles inducing transient permeabilization of surrounding...

chapter

Development of an anatomic heart model for the minimally-invasive closure of the left atrial appendage

Eva C. Graf, Daniel B. Roppenecker, Klaus Tiemann, Victor D. Samper, more

2014 IEEE International Conference on Robotics and Biomimetics (ROBIO 2014) > 607 - 612

2014 IEEE International Conference on Robotics and Biomimetics (ROBIO)

The catheter based minimally-invasive closure of the left atrial appendage for stroke prevention can be realized by placing foldable structures in the heart with the help of a catheter. As a platform for the development and the evaluation of new devices, a phantom was developed that allows to perform the intervention under realistic imaging conditions. The centerpiece of the phantom is an anatomical...

article

The endocannabinoid-CB2 receptor axis protects the ischemic heart at the early stage of cardiomyopathy

Georg D. Duerr, Jan C. Heinemann, Georg Suchan, Elvis Kolobara, more

Basic Research in Cardiology > 2014 > 109 > 4 > 1-15

Ischemic heart disease is associated with inflammation, interstitial fibrosis and ventricular dysfunction prior to the development of heart failure. Endocannabinoids and the cannabinoid receptor CB2 have been claimed to be involved, but their potential role in cardioprotection is not well understood. We therefore explored the role of the cannabinoid receptor CB2 during the initial phase of ischemic...

article

A Large European Multicenter Study

Roxy Senior, Antonella Moreo, Nicola Gaibazzi, Luciano Agati, more

Journal of the American College of Cardiology > 2013 > 62 > 15 > 1353-1361

The purpose of this study was to compare sulfur hexafluoride microbubble (SonoVue)-enhanced myocardial contrast echocardiography (MCE) with single-photon emission computed tomography (SPECT) relative to coronary angiography (CA) for assessment of coronary artery disease (CAD).Small-scale studies have shown that myocardial perfusion assessed by SonoVue-enhanced MCE is a viable alternative to SPECT...

article

Real-time imaging and kinetics measurements of focused ultrasound-induced extravasation in skeletal muscle using SPECT/CT

Pedro Gomes Sanches, Raffaella Rossin, Marcel Böhmer, Klaus Tiemann, more

Journal of Controlled Release > 2013 > 168 > 3 > 262-270

Drugs need to overcome several biological barriers such as the endothelium and cellular membranes in order to reach their target. Promising new therapeutics, many of which are charged and macromolecular, are not able to passively extravasate, let alone cross cell membranes, and stay mainly in the blood pool upon intravenous injection until clearance. Using focused ultrasound (fUS) in combination with...

article

Quantitative Myocardial Contrast Supine Bicycle Stress Echocardiography for Detection of Coronary Artery Disease

Tomasz Miszalski‐Jamka, Stefanie Kuntz‐Hehner, Klaus Tiemann, Krzysztof Karwat, more

Echocardiography > 30 > 4 > 392 - 400

Background: If compared with two‐dimensional echocardiography (2DE), quantitative myocardial contrast echocardiography (MCE) improves detection of coronary artery disease (CAD) during pharmacological stress, but there is paucity of data regarding quantitative MCE performed during supine bicycle stress. Objectives: To determine the feasibility and accuracy of quantitative MCE and assess its incremental...

article

4D phase contrast flow imaging for in-stent flow visualization and assessment of stent patency in peripheral vascular stents – A phantom study

Alexander C. Bunck, Alena Jüttner, Jan Robert Kröger, Matthias C. Burg, more

European Journal of Radiology > 2012 > 81 > 9 > e929-e937

4D phase contrast flow imaging is increasingly used to study the hemodynamics in various vascular territories and pathologies. The aim of this study was to assess the feasibility and validity of MRI based 4D phase contrast flow imaging for the evaluation of in-stent blood flow in 17 commonly used peripheral stents.17 different peripheral stents were implanted into a MR compatible flow phantom. In-stent...

article

Cardiomyocyte-specific deletion of survivin causes global cardiac conduction defects

Jan Wilko Schrickel, Lars Lickfett, Thorsten Lewalter, Klaus Tiemann, more

Basic Research in Cardiology > 2012 > 107 > 6 > 1-12

Survivin (Surv) belongs to the inhibitor of apoptosis protein family. Its cardiac-specific deletion results in reduced cardiomyocyte number, increased cardiomyocyte size and ploidy, and development of heart failure. Its impact on cardiac electrophysiology is unknown. In vivo transvenous electrophysiological studies were carried out in adult male mice with a cardiac-specific deletion of survivin (Surv...

article

Subvalvular hypertrophic calcification of the mitral annulus: [¹⁸F]FDG–PET–CT, MRI, and echocardiography findings

Thorsten Persigehl, David Maintz, Peter Kies, Walter Heindel, more

Journal of Nuclear Cardiology > 2011 > 18 > 2 > 368-370

article

In vivo SPECT/CT imaging of focused ultrasound induced extravasation

Pedro Sanches, Raffaella Rossin, Marcel Böhmer, Klaus Tiemann, more

Nuclear Medicine and Biology > 2010 > 37 > 6 > 722

article

Signifikante Beziehung zwischen weiblichem Geschlecht und einem niedrigeren Grad pathologischer ^99mTc-sestamibi Szintigraphieergebnisse sowie einem höheren Herztod-freien Überleben bei älteren Patienten

Jan Bucerius, Alexius Y. Joe, Ellen Herder, Holger Brockmann, more

Medizinische Klinik - Intensivmedizin und Notfallmedizin > 2010 > 105 > 12 > 901-909

Hintergrund: Ziel der vorliegenden Studie war, einen möglichen Einfluss des weiblichen Geschlechts auf das Ausmaß möglicher myokardialer Perfusionsdefekte in der ^99mTc-sestamibi-Myokardperfusions-Szintigraphie (MPS) und auf neu auftretende kardiale Ereignisse (KE) bei Patienten mit einem Alter ≥ 70 Jahre zu erfassen. Patienten und Methodik: 86 Patienten ≥ 70 Jahre (74,4 ± 3,2 Jahre; Frauen:...

article

Erratum to: Three-dimensional echocardiography and ¹⁵³Sm-EDTMP-SPECT/CT in extensive cardiac metastases from osteosarcoma

Klaus Tiemann, Jörg Stypmann, Federico Landeta, Stefanie Wiebe, more

European Journal of Nuclear Medicine and Molecular Imaging > 2010 > 37 > 12 > 2407-2407

The online version of the original article can be found at http://dx.doi.org/10.1007/s00259-010-1592-0 .

article

Three-dimensional echocardiography and ¹⁵³Sm-EDTMP SPECT/CT in extensive cardiac metastases from osteosarcoma

Klaus Tiemann, Jörg Stymann, Federico Landeta, Stefanie Wiebe, more

European Journal of Nuclear Medicine and Molecular Imaging > 2010 > 37 > 12 > 2406-2406

An erratum to this article can be found at http://dx.doi.org/10.1007/s00259-010-1623-x

article

Myocardial Contrast Echocardiography Enhances Long-Term Prognostic Value of Supine Bicycle Stress Two-Dimensional Echocardiography

Tomasz Miszalski-Jamka, Stefanie Kuntz-Hehner, Harald Schmidt, Daniel Peter, more

Journal of the American Society of Echocardiography > 2009 > 22 > 11 > 1220-1227

The aim of this study was to determine the incremental prognostic value of myocardial contrast echocardiography (MCE) over two-dimensional echocardiography (2DE) in patients undergoing supine bicycle stress.Eighty-four patients with known or suspected coronary artery disease who underwent supine bicycle stress with 2DE and MCE (mean age, 58.5 ± 9.7 years; 68 men) were followed up for 48.3 ± 8.9 months...

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INFONA - science communication portal

Search results for: Klaus Tiemann

Imaging in CHD—who runs the show: Editorial to “congenital anatomy, acquired pathology—a synergistic approach to echocardiographic evaluation of the adult with congenital heart disease”

ECHOCARDIOGRAPHY: A Journal of Cardiovascular Imaging and Intervention

A planning system of the implant size and position for minimally-invasive closure of the left atrial appendage

Histogram-Based Optical Flow for Functional Imaging in Echocardiography

Imaging in Cardiovascular Research

Soluble Flt-1 links microvascular disease with heart failure in CKD

Ultrasound-mediated gene delivery of naked plasmid DNA in skeletal muscles: A case for bolus injections

Development of an anatomic heart model for the minimally-invasive closure of the left atrial appendage

The endocannabinoid-CB2 receptor axis protects the ischemic heart at the early stage of cardiomyopathy

A Large European Multicenter Study

Real-time imaging and kinetics measurements of focused ultrasound-induced extravasation in skeletal muscle using SPECT/CT

Quantitative Myocardial Contrast Supine Bicycle Stress Echocardiography for Detection of Coronary Artery Disease

4D phase contrast flow imaging for in-stent flow visualization and assessment of stent patency in peripheral vascular stents – A phantom study

Cardiomyocyte-specific deletion of survivin causes global cardiac conduction defects

Subvalvular hypertrophic calcification of the mitral annulus: [¹⁸F]FDG–PET–CT, MRI, and echocardiography findings

In vivo SPECT/CT imaging of focused ultrasound induced extravasation

Signifikante Beziehung zwischen weiblichem Geschlecht und einem niedrigeren Grad pathologischer ^99mTc-sestamibi Szintigraphieergebnisse sowie einem höheren Herztod-freien Überleben bei älteren Patienten

Erratum to: Three-dimensional echocardiography and ¹⁵³Sm-EDTMP-SPECT/CT in extensive cardiac metastases from osteosarcoma

Three-dimensional echocardiography and ¹⁵³Sm-EDTMP SPECT/CT in extensive cardiac metastases from osteosarcoma

Myocardial Contrast Echocardiography Enhances Long-Term Prognostic Value of Supine Bicycle Stress Two-Dimensional Echocardiography

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