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Nefazodone is an anti-depressant that interacts with a wealth of pharmacological targets, including some that may exert anti-dyskinetic and anti-psychotic effects in Parkinson’s disease (PD), notably serotonin 1A and 2A receptors. In this study, we sought to determine the effect of nefazodone on l-3,4-dihydroxyphenylalanine (l-DOPA)-induced dyskinesia and psychosis-like behaviours (PLBs) in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine...
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