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The recent development of imaging and image processing techniques, such as 4D microscopy and 3D cell tracking, enables analysis through quantification of the movement of large cell populations invivo. These imaging approaches provide an opportunity to study embryonic morphogenesis during development from the level of cellular processes to the scale of entire organism. Image analysis reveals cell...
The effective treatment of cartilage defects by tissue engineering requires an improved understanding of the effect of mechanical forces on cell differentiation within three-dimensional (3D) matrices. The objective of this study was to investigate the effects of mechanical constraint and cyclic tensile strain on the chondrogenic differentiation of mesenchymal stem cells (MSCs) in a 3D collagen type...
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